Cell Lines and Cell Cultures
Thermo Scientific™ GeneBLAzer™ FXR-UAS-bla HEK 293T Cells
FXR-UAS-bla HEK 293T 293 cells contain the ligand-binding domain (LBD) of the human farnesoid X receptor (FXR) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ CellSensor™ LEF/TCF-bla HCT-116 Cell Line
Wnt signaling via Beta-catenin plays a central role in development and homeostasis. This pathway is invariably disrupted in colorectal tumors and commonly affected by mutation in other cancers.
Thermo Scientific™ CellSensor™ TNFa-bla THP-1 Cell Line
Tumor necrosis factor-alpha (TNFα) cytokine cell signaling is a critical pathway involved in immune and inflammatory responses. In addition, TNFα has been shown to inhibit growth and induce differentiation in tumor and non-tumor cells.
Thermo Scientific™ CellSensor™ GAS-bla ME-180 Cell Line
The CellSensor™ GAS-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Gamma Activated Sequence (GAS) response element stably integrated into ME-180 cells.
Thermo Scientific™ Tango™ TBXA2R-bla U2OS Cells
The Tango™ TBXA2R-bla U2OS cells contain the human Thromboxane A2 Receptor (TBXA2R) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ STAT6-bla RA-1 Cell Line
The CellSensor™ STAT6-bla RA-1 Cell Line contains a beta-lactamase reporter gene under control of the STAT6 response element stably integrated into Ramos-1 (RA-1) cells.
Thermo Scientific™ CellSensor™ C/EBP-bla FreeStyle™ 293F Cell Line
CCAAT/enhancer-binding protein (C/EBPa basic leucine zipper transcription factor, is involved in the regulation of mitotic growth arrest and differentiation.
Thermo Scientific™ CellSensor™ ISRE-bla HEK293T Cell Line
The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.
Thermo Scientific™ CellSensor™ NFκB-bla RA 1 Cell Line
The CellSensor™ NFκB-bla RA-1 cell line contains a beta-lactamase reporter gene under control of the NFκB response element stably integrated into Ramos 1 (RA-1) cells.
Thermo Scientific™ CellSensor™ irf1-bla Ba/F3 Cell Line
Jak/Stat signaling pathways play essential roles in the cellular responses to distinct cytokines.
Thermo Scientific™ CellSensor™ SBE-bla HEK 293T Cell Line
Smad cell signaling is a critical pathway involved in cell growth and proliferation.
Thermo Scientific™ CellSensor™ ISRE-bla Jurkat Cell Line
The CellSensor™ ISRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of the interferon-stimulated response element (ISRE) stably integrated into Jurkat cells.
Thermo Scientific™ CellSensor™ AP-1-bla HEK293T Cell Line
The CellSensor™ AP-1-bla HEK 293T Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into HEK 293T cells.
Thermo Scientific™ CellSensor™ SBE-bla A375 Cell Line
Bone morphogenetic proteins (BMPs), members of the transforming growth factor beta (TGF-β) superfamily, play important roles in the development of the heart, central nervous system and cartilage.
Thermo Scientific™ Tango™ HRH3-bla U2OS Cells
The Tango™ HRH3-bla U2OS cells contain the human Histamine Receptor H3 (HRH3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.