Cell Lines and Cell Cultures
Thermo Scientific™ LanthaScreen™ PRAS40 293E Cell Line
The PI3K/AKT pathway is activated by various stimuli (including insulin and IGF-1) and mediates signals for cell growth, cell survival, translation, and inhibition of apoptosis.
Thermo Scientific™ Tango™ RLN3R1-bla U2OS Cells
The Tango™ RLN3R1-bla U2OS cells contain the human Relaxin/Insulin-like Family Peptide Receptor 3 (RLN3R1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ FPRL-1-Gα15-NFAT-bla CHO-K1 Cells
GeneBLAzer™ FPRL-1-Gα15-NFAT-bla CHO-K1 cells contain the human Formyl Peptide Like Receptor 1 (FPRL-1) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ GPR119-bla U2OS Cells
The Tango™ GPR119-bla U2OS cells contain the human G-protein Coupled Receptor 119 (GPR119) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ CXCR4-bla U2OS Cells
The Tango™ CXCR4-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 4 (CXCR4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ OPRL1-bla U2OS Cells
The Tango™ OPRL1-bla U2OS cells contain the human Opioid Receptor-Like 1 (OPRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ RARγ-UAS-bla HEK 293T Cells
The GeneBLAzer™ RAR gamma-UAS-bla HEK 293T cells contain the ligand binding domain (LBD) of the human retinoic acid receptor gamma (RAR gamma) fused to the DNA-binding domain of GAL4, stably integrated in the GeneBLAzer™ UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ SCTR-CRE-bla CHO-K1 Cells
GeneBLAzer™ SCTR-CRE-bla CHO-K1 cells contain the human Secretin Receptor (SCTR) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ SIE-bla HEK293T Cell Line
The CellSensor™ SIE-bla HEK 293T cell line contains a beta-lactamase reporter gene under control of the SIE response element stably integrated into HEK 293T cells.
Thermo Scientific™ GeneBLAzer™ NMUR1-NFAT-bla CHO-K1 Cells
GeneBLAzer™ NMUR1-NFAT-bla CHO-K1 cells contain the human Neuromedin U-25 receptor 1 (NMUR1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ CALCR -CRE-bla FreeStyle™ 293F Cells
The GeneBLAzer™ CALCR-CRE-bla Freestyle293 cells contain the CALCR receptor isoform (CTR2/CT(a)/CTRI1-), Accession No. NM_001742.2, stably integrated into the CellSensor™ CRE-bla Freestyle293 cell line.
Thermo Scientific™ GeneBLAzer™ EDG3-Gα15-NFAT-bla HEK 293T Cells
GeneBLAzer™ EDG3-Gα15-NFAT-bla HEK293T cells contain the human Endothelial Differentiation Receptor 3 (EDG3) stably integrated into the GeneBLAzer™ EDG3-Gα15-NFAT-bla HEK293T cell line.
Thermo Scientific™ UAS-bla HEK 293T Master Cell Line
The UAS-bla HEK 293T Master Cell Line consists of HEK 293T cells stably transfected with a UAS-bla fusion construct.
Thermo Scientific™ GeneBLAzer™ HCRTR2-Gα15-NFAT-bla CHO-K1 Cells
GeneBLAzer™ HCRTR2-Gα15-NFAT-bla CHO-K1 cells contain the human Orexin Receptor B (HCRTR2) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ NPY5R-bla U2OS Cells
The Tango™ NPY5R -bla U2OS cells contain the human Neuropeptide Y Receptor Y5 (NPY5R) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.